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CHEMICAL:
Vinpocetine 5mg (Molecular formula C22H26N2O2), excipient, lactose, S.C.
DESCRIPTION:
Vinpocetine is a new cerebral metabolic activator which can improve cerebral circulation and enhance oxygen and glucose utilisation in the brain. Vinpocetine diminishes or reduces disturbances due to hypoxia or to deficient cerebral metabolism. Vinpocetine produces improvement in mental and neurological symptoms which are sequelae to cerebral haemorrhage, cerebral infarction (particularly multi- infarct) and cerebrosclerosis. Cerebral circulation is particularly enhanced in response to low oxygen levels in the brain and thus increased blood flow to the brain is not accompanied by reduced peripheral blood flow and side effects associated with that as hypertension. Vinpocetine improves oxygen and glucose utilisation by brain cells and increases their resistance to damage by hypoxia.
CHARACTERISTICS:
- Vinpocetine improves oxygen utilisation by brain tissue and increases it's resistance to damage during hypoxia.
- Vinpocetine selectively increases cerebral circulation and decreases cerebral vascular resistance.
- With minimal systemic effects, Vinpocetine does not alter pulse rate, blood pressure or respiration rate.
- With possible anti-platelet effect, Vinpocetine can reduce the possibilities of thrombus formation in the constricted vessels.
- Vinpocetine is well tolerated clinically.
INDICATION:
Improvement of symptoms caused by following diseases; Sequelae of cerebral haemorrhage, sequelae of cerebral infarction, cerebrosclerosis.
DOSAGE:
One tablet (5mg each) 3 times a day.
PRECAUTIONS, SIDE EFFECTS AND CONTRAINDICATIONS:
Vinpocetine is contradicted in those patients thought to be incomplete homeostasis after cerebral haemorrhage. Vinpocetine is contradicted in women who are or may become pregnant. 2. Side effects. Hypersensitivities; Eruption; Nausea. If hypersensitive signs occur the drug should be discontinued immediately. Gastrointestinal system; Anorexia, abdominal pain, diarrhoea may be occurred rarely. Circulatory system; Erythroposopalgia, excitation may be occurred rarely. Blood; Leukocytopenia may be occurred rarely. Liver; Parameters SGOT or SGPT may be risen rarely. Kidney; Parameter of BUN may be risen rarely. 3. Precaution. In animal studies reproductive toxicity such as foetus death, abortion was reported, therefore the drug should be forbidden in women who are or may become pregnant. In animal studies Vinpocetine can be crossed to breast milk, therefore drug should not be used by women who are lactating.
STORAGE AND SHELF LIFE:
Tight container protected from light. Store at room temperature 3 years.
| The above information is the translation of the manufacturer's insert. It is provided under the supplying company's terms and conditions and should not replace the advice of your personal physician. |
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