Articles under Melatonin


  • The Pineal Clock, Cancer and Melatonin

    The pineal clock, cancer and melatonin Cancer and non-cancer; strategies for early detection, prevention and cure of neoplastic processes By Walter Pierpaoli, M.D.   I propose here that cancer, similarly to most diseases such as cardiovascular, autoimmune and neurodegenerative diseases is simply, in most cas...
  • The Therapeutic Effects of High-Dose Melatonin Administration

    The therapeutic effects of high-dose melatonin administration By Jesus A.F. Tresguerres1, M.D, Ph.D.   This article reviews the effects of high-dose melatonin administration on several diseases. Experimental studies performed over more than 20 years have shown that oxidative stress and inflammation increase in nearly all tissues with many degenerative diseases or aging. We have measured several parameters related to oxidative stress, inflammation...
  • Who Is Afraid Of Health?

    Who Is Afraid Of Health? Known throughout the world for his discoveries related to melatonin, to the pineal gland and to immunological identity, the author openly denounces the obstructionism by the pharmaceutical cartel to accessing really effective therapies for restoring health and preventing the onset of degenerative diseases. Foreword Such an unlikely question finds prompt answers which everyone awaits or senses. These obvious answers are in everyone's mind, b...
  • How to Maintain or Even Improve Your Vision as You Age

    How to Maintain or Even Improve Your Vision as You Age Vision may be the most precious of our five senses. Yet most of us may take it for granted...until it begins to deteriorate with age. As we get older we likely need greater amounts of light to perceive details clearly, and reading glasses to discern fine print which would otherwise be fuzzy. Night driving becomes difficult due to sensitivity from bright lights and glare, and it's challenging to visually adapt to the darkness. Th...
  • Is Reversing Aging Degenerate?

    Is Reversing Aging Degenerate? By Dr. Richard Lippman Since the serialization of Oscar Wilde’s novel “The Picture of Dorian Gray” in the 1890s, the idea of staying forever young while an oil painting grew older was condemned as degenerate. Indeed, several years later Wilde was imprisoned for his alleged degeneracies. Then, in 1945, Albert Lewin’s film adaptation of the novel was poorly received given the attitudes about aging and morality at that time. In 19...
  • A clash between a frustrated medical community and alternative medicine

    A clash between a frustrated medical community and alternative medicine For more than 25 years, the American medical community has been dismayed by an ever-increasing number of patients who turn to alternative medicine for treatment. Indeed, more than half of sick Americans seek alternative doctors, such as naturopaths, and few of these patients discuss their treatments with their conventional doctors. This phenomenon is especially true of chronic sufferers of cancer, chroni...
  • The rotational theory of aging

    The rotational theory of aging An interview with Walter Pierpaoli, M.D., PhD. In this interview, the Editor of the Aging Matters™ magazine, Phil Micans (PM) interviews Walter Pierpaoli, M.D., Ph.D. (WP) Dr Pierpaoli is famous for his scientific and clinical published research into melatonin, the thymus,...
  • Is Your Brain Clearing Beta-Amyloid, the Leading Cause of Alzheimer’s and Parkinson’s?

    Is Your Brain Clearing Beta-Amyloid, the Leading Cause of Alzheimer’s and Parkinson’s? “When we skip sleep, we may be doing irreparable damage to the brain prematurely aging it. . .” M. Nedergaard, MD Until a few years ago, scientists thought that the brain did its own cleaning and recycling of waste both day and night. However, Professor Steven Coles of Stanford University has established that beta amyloid clearance in seniors is highly inefficient and incom...
  • Is Your Brain Clearing Beta-Amyloid, the Leading Cause of Alzheimer’s and Parkinson’s?

    Is Your Brain Clearing Beta-Amyloid, the Leading Cause of Alzheimer’s and Parkinson’s? “When we skip sleep, we may be doing irreparable damage to the brain prematurely aging it. . .” M. Nedergaard, MD Until a few years ago, scientists thought that the brain did its own cleaning and recycling of waste both day and night. However, Professor Steven Coles of Stanford University has established that beta amyloid clearance in seniors is highly inefficient and incom...
  • The Grim Reaper Came Knocking and I Answered by Correcting my Hormones and Peptides!

    The Grim Reaper Came Knocking and I Answered by Correcting my Hormones and Peptides! By Dr. Richard Lippman Death came calling when I suffered a minor arrhythmia. My damaged youth started when my close friends pushed me aside and sometimes retorted with irritating comments. I hadn’t realized how negative I had become and its unwelcome effects upon my friends. My neurosurgeon colleague diagnosed me with Asperger’s syndrome (a form of autism), but he had only part...
  • Avoiding A Hospital Bed

    Avoiding A Hospital Bed My biochemist friend and patient, Bob, phoned me recently. In an urgent voice, he requested an immediate appointment. I was a bit surprised because several times previously he wanted to use only his traditional physician, who was covered by his medical insurance. I made the appointment for the following afternoon, wondering why Bob suddenly wanted my help. The next day, Bob arrived in my office, flustered and haggard from lack of sleep. He explained t...
  • The Nuts and Bolts of Aging Part Two

    The nuts and bolts of aging: Part two (Waking up our vital cells with hormones and anti-cancer–inducing nutrients) In Part one of this article, I established that our potential lifespans are determined by repair mechanisms that kick into effect during our mid-twenties. At this benchmark, the aging process starts because random molecular damages begin to exceed repairs. Therefore, we should be examining the underlying causes of aging and the consequent repair of our disintegrating ...
  • The Nuts and Bolts of Aging Part Two

    The nuts and bolts of aging: Part two (Waking up our vital cells with hormones and anti-cancer–inducing nutrients) In Part one of this article, I established that our potential lifespans are determined by repair mechanisms that kick into effect during our mid-twenties. At this benchmark, the aging process starts because random molecular damages begin to exceed repairs. Therefore, we should be examining the underlying causes of aging and the consequent repair of our disintegrating ...
  • Beyond diet and lifestyle, the route to a cleaner, fitter and healthier you

    Beyond diet and lifestyle, the route to a cleaner, fitter and healthier you This article has been written specially for a new book called “Great teeth for Life” authored by Britain’s leading alternative dentist, Dr.Brian Halvorsen. The book is available through IAS –Why supplements ...
  • Melatonin Zn Se age related macular degeneration

    Melatonin Zn Se and Age Related Macular Degeneration Age-related macular degeneration (ARMD) is the leading cause of severe visual loss in older people, indeed it is the main cause of central vision loss (blindness) in the USA today for those over the age of fifty; (Source: American Academy of Ophthalmology). Macular degeneration is a condition whereby the light sensing cells in the eye’s macula malfunction and eventually they cease to work. Often individuals with mac...
  • Interview with Walter Pierpaoli, M.D. about melatonin and TRH

    Interview with Walter Pierpaoli, M.D. about melatonin and TRH Born in 1934, Dr. Walter Pierpaoli is one of the world’s eminent researchers in the field of aging and cancer. He is perhaps best known for his research in the field of melatonin and its effects on aging, sleep patterns, cancer, jet lag, fertility and immunity (to name a few). His efforts to promote these facts through his scientific and clinical publications and also th...
  • The Cataract Cure about L-carnosine and N-acetylcarnosine

    The Cataract Cure about L-carnosine and N-acetylcarnosine Dr. Kyriazis is one of Britain’s top anti-aging physicians and is internationally recognised as a pioneer in the field. He is a bio-gerontologist with a medical degree and postgraduate degrees from King’s College, London and the Royal College of Physicians. He has written many books for both ...
  • Health care bogged down by ‘old think’

    Health care bogged down by ‘old think’ Practical mindedness avoids ‘Old Think’ For the last three hundred years, Americans have been admired for their practical mindedness. For example, in the middle of the eighteenth century, Benjamin Franklin established an efficient postal and public library system that allowed rapid dissemination of news and information throughout the colonies. Other countries had no such systems and no interest in a more literat...
  • Insomnia cured at last

    Insomnia cured at last Lack of sleep causes weight gain¹ and a host of other health problems² and until 2011, the medical community has only addressed its symptoms with prescription drugs loaded with side effects. For example, five years ago Rep. Robert F. Kennedy Jr. took Ambien® at bedtime, and five hours later, he almost ran down a DC cop thinking it was time to go to work at 3:00 am! Why Treat Symptoms Of Insomnia? Why Not Solve Its Underlying Causes? Other ...
  • Application of smart drugs - for enhanced health and longevity

    Application of smart drugs - for enhanced health and longevity Is the new film Limitless fiction or fact? ‘Limitless,’ the movie, is explained by the following synopsis. A young writer has been down-and-out on this luck for several years. He has writer’s block, thus he cannot complete his half-finished novel. He is threatened with eviction from his apartment, his girlfriend leaves him, and he mope...
  • The Pineal Clock And Cancer

    The Pineal Clock And Cancer Abstract Cancer and non-cancer, strategies for early detection, prevention and cure of neoplastic processes - Abstract I propose here that cancer, similarly to most diseases such as cardiovascular, autoimmune and neurodegenerative diseases is simply, in most cases, the final expression of an early or late derangement of central neuro-endocrine-immune control, defined now as ‘immunological surveillance’, leading to a loss of non-prolifera...
  • Melatonin A Universal Guardian?

    Melatonin A Universal Guardian? The role of Melatonin in hormonal regulation and ageing has been described and reviewed in an elegant way by Pierpaoli in his book “The Key of Life” (2007). The fact remains that this molecule seems to be Universally conserved across animal but also plant species; this fact alone should draw attention to its likely universal importance.It was named melatonin because of its ability in certain fish, reptiles and amphibians to lighten ski...
  • New Method of Improved BHRT

    (Bioidentical Hormone Replacement or Corrective Therapy)Understanding Pharmacokinetics Allows Optimal Hormone Replacement By Doctors Richard Lippman and Russell Laudon Mother Nature employs a “pulsing schedule” in our endocrine glands Taking hormones and nutrients only once a day does not promote optimal health. Ideally, we should consume them six times daily since Mother Nature employs this “pulsing schedule” in our endocrine glands...
  • The Essential Cyclicity of Life

    The Essential Cyclicity of Life (The Discovery of the Pineal Life Clock) Ed.- Dr. Pierpaoli is one of the few really serious academic scientists who is interested and determined to pursue anti-aging medicine and prevent aging itself. Indeed, his work speaks for itself, as he is the man who introduced the concept of melatonin to the world through the initial research and his best selling book - The Key of Life ...
  • Synergistic Programs - Eye Care pack

    Don’t let your vision age Eye sight is clearly one of the most important senses that we possess and if we were somehow forced to have to do without one or more of our senses, eye-sight would probably be the one that would be most “missed.” As we age a number of processes take place that affect our eye-sight, principally there is an increase in the prevalence of free radicals and at the same time there is a decline in the availability of antioxidants and in the efficien...
  • Preventing skin damage from radiotherapy (the benefits of topical Melatonin)

    Preventing skin damage from radiotherapy (the benefits of topical Melatonin) Radiotherapy is commmonly used in the treatment of cancer. It is the primary curative modality in about 30% of patients, and more than half of all cancer patients recieve radiation therapy sometime during the course of their disease. Similar to surgery, radiation therapy is a local-regional modality. When successful, this treatment cures, (by eradicating tumor in the primary side), the draining regiona...
  • MELATONIN: The Miracle Molecule

    MELATONIN: The Miracle Molecule What is melatonin? In our bodies, melatonin is the molecule naturally produced within the pineal gland, the glandular organ nestled between the cerebral hemispheres that the great French philosopher Descartes once proposed to be the "seat of the soul." We find melatonin everywhere in the biological world, from unicellular organisms to the vertebrates. Melatonin is the “Master Hormone-Modulating Molecule” but it is misleading...
  • Interview With Walter Pierpaoli M.D., Ph.D.

    Interview With Walter Pierpaoli M.D., Ph.D. Walter Pierpaoli, M.D., is one of the great avant-garde professional researchers and physicians today who are searching for the central cure for aging disorders. He describes himself thus: "I am not a wizard or a sorcerer but simply a man curious of nature and biology who has spent almost 40 well documented years in the merry companionship of mice, waiting for them to teach me how and why we age and die. My main feature i...
  • How to Stop Aging: Melatonin and the Pineal Gland

      How to Stop Aging?   [Ed. Dr. Pierpaoli is one of the world's leading neuroendocrine researchers and it was his work that has made melatonin "common knowledge" throughout the world. However, as you will read in this article, Dr. Pierpaoli's research about melatonin goes far beyond its use just for sleep, jet-lag and as an anti-oxidant. In-fact, Dr. Pierpaoli's ground-breaking work suggests that melatonin is a crucial factor in the treatment for aging it...
  • Synergistic Programs - Anxiety & Stress

    Synergistic Programs - Anxiety & Stress Stage 1:Picamilone tablets: 50mg 2 or 3 times daily provides a unique combination of GABA and niacin (vitamin B3) bonded. This combination has been proven not only to calm and placate stressed individuals (probably through the action of GABA), but at the same time there is no sedative effect as is often the case with anti-anxiety products. Instead through the action of niacin, picamilone actually helps to ...
  • Synergistic Programs - Sleep Improvement

    Synergistic Programs - Sleep Improvement Stage 1:Melatonin tablets: 3mg to 6mg at bedtime. Melatonin helps to rebalance the circadian rhythms (the day-night cycle), as a result deeper REM sleep is improved and the individual feels more refreshed the following day. Remember that light entering the eye destroys melatonin, so it is important to be in bed, in darkness within 15-minutes of taking the melatonin.L-Tryptophan ca...
  • Synergistic Programs - Cancer

    Synergistic Programs - Cancer This program is aimed at those more concerned about preventing cancer than treating it. Please see the cross-reference list and cancer articles for further information regarding treatment. Stage 1:Cell Stat Plus: capsules 2 or 3 times daily Cell Stat Plus contains both resveratrol and quercetin, the major flavonoids found in the skins of red grapes. It is known that they can prevent the growth of cells deriv...
  • Synergistic Programs - Antiaging pack

    Synergistic Programs - Antiaging pack Antiaging is the ultimate preventative medicine As you might expect, antiaging medicine is by definition an incredibly broad subject. The American Academy of Antiaging Medicine (A4M) essentially defines it as the best of all the existing and emerging technologies, which can naturally mean a huge field. Here at IAS, whilst we can accept that there are many approaches to improving aging, from a walk round the block (e.g. exer...
  • Synergistic Programs - frequent fliers

    Synergistic Programs - Frequent Fliers Stage 1:Melatonin tablets: To overcome jet-lag, melatonin is best taken at approximately 10pm to 12pm of the time of the destination for a few days before your flight. For example if you are flying from New York to London (with a 5-hour time difference in advance), then whilst in New York you should take 3mg of melatonin between 5pm and 7pm local time for 2-3 days prior to your flight. This will be equivil...
  • Melatonin Prolongs Life

    Melatonin Prolongs Life (Ed.- Dr. Pierpaoli would like readers to know that this article has been assembled for people who can appreciate its simplicity, and not for those "experts" whose minds allow no penetration of the simple and smart laws of Nature). Emmy's Story My mother-in-law; Emmy Hugly, living near Lucerne in Switzerland, is now 94 years-old, perfectly healthy and Parkinson-free in the last 15 years, with no intention to give up! Her story ...
  • Synergistic Programs - Immune System Enhancement

      Synergistic Programs - infection and the immune system   Stage 1:Biostim tablets: 1 mg. 2 times a day for 8-days, a 3-week break. Then 1 mg. a day for 8-days followed by a further 3-week break, finally 1 mg. a day for 8-days. This cycle can last for up to 12-months, although if you are very prone to infections it may be repeated at 3 to 6-month intervals. Biostimâ increases the production of white blood cells and in so doing...
  • Aging and Immunity by James South

    Aging and Immunity We live in a world of entropy. Entropy is the tendency of complex structures to gradually decay or break down with time. Entropy is one of the brute facts of existence. It is "codified" as one of the basic laws of physics: the second law of thermodynamics, which governs both living and inanimate matter. We humans normally call the process of entropy "ageing." The anti-ageing movement is literally an anti-entropy movement. Modern science has discovere...
  • Synergistic Program - Age Prevention

    What is the best way to tackle aging? How can we prevent aging’s annoyances from becoming disorders and diseases? We’ve done our best to simplify the answers for you by breaking down the protocols and products into 4 categories. We hope that you enjoy reading about this program and t...
  • Synergistic Programs - Depression & Well being

    Synergistic Programs - Depression & Well being Stage 1:5HTP capsules: One capsule (50mg) 1 to 3 times daily, ideally taken with food. 5HTP or 5-hydroxy-tryptophan is the most potent form of tryptophan that is exclusively used by the brain. As the direct precursor to serotonin 5HTP can elevate its levels and thus alleviate depression. Clinical trials have suggested that 5HTP is as effective as Prozac.Gerovital tablets: On...
  • Age Related Macular Degeneration (AMD)

    Age related macular degeneration (AMD) leads to the loss of your central vision, affecting your ability to read, write and drive.AMD generally affects people over the age of 50 and occurs in around a third of all people aged over 75. There are two types of AMD – dry and wet. Dry AMD occurs in approximately 90 per cent of cases and is the least easy to recognise. This is because it develops gradually, whereas, Wet A...