Articles under Oxaloacetate


  • Antioxidant Extends Lifespan

    The National Institute on Aging (NIA) announced the final results of testing from three government labs regarding the patented antioxidant nordihydroguaiaretic acid (NDGA). All three labs agreed that NDGA extended lifespan by a resounding 12% in mice (1) (see Figure 1).Figure 1: The survival plots for m...
  • Antioxidant Extends Lifespan

    The National Institute on Aging (NIA) announced the final results of testing from three government labs regarding the patented antioxidant nordihydroguaiaretic acid (NDGA). All three labs agreed that NDGA extended lifespan by a resounding 12% in mice (1) (see Figure 1).Figure 1: The survival plots for m...
  • Updating the Calorie Restriction Mimetics

    Updating the Calorie Restriction Mimetics When I first started writing about Calorie Restriction Mimetics (CRM) 10 years ago, research in this area was at its infancy. Now however, several CRM are well-known and relatively well-accepted agents which imitate the effects of calorie restriction itself. I highlight the fact that these compounds are not merely pills for those who are too lazy to diet, but may be used (under medical supervision) in association with a healthy lifestyle to ...
  • mTOR Inhibitors in Cancer, Aging and Health

    mTOR Inhibitors in Cancer, Aging and Health Marios Kyriazis MD When it comes to the regulation of aging mechanisms, one important molecule which has widespread effects is mTOR. This is the acronym of the mechanistic (previously also called ‘mammalian’) Target Of Rapamycin. It is a protein kinase which regulates the proliferation and development of cells. mTOR acts as a central controller in signalling pathways which regulate the survival and function of the cell...