Articles by SOUTH, MA, James


  • Vinpocetine, The Superior Cerebral Enhancer And Protector

      Vinpocetine, The Superior Cerebral Enhancer And Protector By James South MA   Vincamine (VCM) is an alkaloid extracted from the Periwinkle plant, Vinca minor. Vinpocetine (VPC) is produced slightly altering the VCM molecule. VPC is more technically referred to as "ethyl apovincaminate." VCM and VPC have been widely researched and used clinically for over 25 years, in disorders ranging from cerebral arteriosclerosis and senile dementia, to Meniere's di...
  • Thymus Gland - Its Overlooked But Vital Role

    Thymus Gland - Its Overlooked But Vital Role The thymus gland (TG) is a small gland in the upper chest. It weighs one third - to one half ounce at birth, and reaches its peak weight of about 1 ounces at puberty. Thereafter, under the influence of many factors, including adrenal and sex hormones, the active TG cells begin to die off, with much of the TG tissue being gradually replaced by fat and connective tissue. Much of the healthy TG structure typically atrophies by a...
  • L-Dopa: It's more than an anti-Parkinson drug

    L-Dopa: It's more than an anti-Parkinson drug L-dopa, also known as Levodopa and L-3, 4-dihydroxyphenylalanine (1), is best known to the world as a treatment for Parkinson’s disease (PD), a neurological disorder. Indeed, as Hauser and Zesiewicz remark: “L-dopa and peripheral decarboxylase inhibitor (PDI) (Sinemet) therapy remains the gold standard for symptomatic treatment for PD. It provides the greatest anti-Parkinsonian benefit with the fewest side effects” (2). Yet e...
  • Mild Silver Protein and its Effectiveness Against Internal and Topical Infections

    Mild Silver Protein and its Effectiveness Against Internal and Topical Infections - Hi Ho Silver Away! Silver (Ag) is atomic element number 47, with an atomic weight of 108. It is one of the so-called 'heavy metals', along with lead, mercury, cadmium and gold. Yet unlike its heavy metal cousins, Ag is surprisingly non-toxic to humans and animals. And unlike the other heavy metals, Ag has a long history of successful medical and public health use dating back 6000 years! ...
  • Anthrax

    Important Announcement: Viruses, Super-Germs, Anti-Biotics and Silver In these delicate and dangerous times to be forewarned is forearmed. At present needs may dictate that some protection is readily available against the possibility of the release of potent super-germs and viruses such as bird flu. IAS is currently offering a wide range of anti-biotics that may be “kept at the ready” and unsurprisingly demand around the western world is high. Classically m...
  • SAMe - The Ultimate Nutrient For Mood, Liver, Heart, Joint And Brain Protection

    SAMe - The Ultimate Nutrient For Mood, Liver, Heart, Joint And Brain Protection S-Adenosylmethionine, more popularly known as "SAMe", is hardly a household word, even among life-extension and anti-aging medicine enthusiasts, yet its pivotal importance in human health and biochemistry is hard to over-estimate. As SAMe research pioneer G. Stramentinol notes; "[SAMe] is an important physiologic compound that occurs in every living cell... SAMe is probably second only to ATP in the...
  • Centrophenoxine: A true life extension drug?

      Centrophenoxine: A true life extension drug? By James South MA   Centrophenoxine (CPH), also known as meclofenoxate, is one of the oldest nootropic drugs still in use - it was developed in 1959 at the French National Scientific Research Center (1). CPH is a compound (ester) of two biochemical's: dimethylaminoethanol (DMAE) and parachlorophenoxyacetic acid (PCPA) (see Fig. 1) (1). DMAE occurs naturally in some foods, especially fish, and is also a naturally ...
  • Centrophenoxine - The Neuroenergizer

    Centrophenoxine - The Neuroenergizer Centrophenoxine, also known as centrophenoxine (CPX), is one of the original anti-aging, neuro-energizing drugs. It has been studied and used clinically for over 30 years. CPX is a compound of two biochemicals- diethylaminoethanol (DMAE) and parachlorophenoxyacetate (pCPA). DMAE is a natural food component, found especially in fish, and is also a natural metabolite of the human body, CPX's other half, pCPA, is a synthetic compound si...
  • Centrophenoxine - The Anti-Aging Brain Booster

    Centrophenoxine - The Anti-Aging Brain Booster Centrophenoxine, also known as Lucidril, is one of the original anti-aging, neuro-energizing drugs. It has been studied and used clinically for over 30 years. Centrophenoxine is a compound of two biochemicals – dimethylamineoethanol (DMAE) and parachlorophenoxyacetate (pCPA). DMAE is a natural food component, found especially in fish, and is also a natural metabolite of...
  • Resveratrol and Quercetin - Anti Heart and Anti Cancer Dynamic Duo

      Resveratrol and Quercetin - Anti Heart and Anti Cancer Dynamic Duo By James South MA   Heart disease and cancer are the two main causes of death in America and Europe, eventually killing about 2/3 of all adults. For the past 40 years, it has been virtually a dogma of Western medicine that a diet high in saturated fat/cholesterol, and/or a high blood cholesterol level, is the primary cause of heart disease. The high blood cholesterol so typical of West...
  • Pyritinol - The Antioxidant, Immune-Enhancing, Anti-Rheumatoid Arthritis Nootropic

    Pyritinol - The Antioxidant, Immune-Enhancing, Anti-Rheumatoid Arthritis Nootropic Pyritinol (PYR) is perhaps the oldest nootropic drug which is still in use - it has been continuously used and researched in Europe since it was patented by Merck in 1961. Surprisingly for a drug whose patent expired in the late 1970's PYR has generated as much published research in the 1980's and 1990's as was generated in the early years of PYR studies. This seems to be due to the wide ...
  • Reducing Stress And Increasing Productivity With Pregnenolone

    Reducing Stress And Increasing Productivity With Pregnenolone Pregnenolone is a natural; body produced metabolite made from cholesterol. It is synthesized inside the mitochondria, the tiny "power plants" (up to 1000's per cell) found in each cell. Pregnenolone is the basic precursor, or starting raw material, for the production of ALL the human steroid hormones, including DHEA, progesterone, estrogen, testosterone, cortisol and aldosterone, but pregnenolone is not itself stero...
  • Piracetam - The Original Nootropic

    Piracetam - The Original Nootropic It was originally used to treat motion sickness. (1) Between 1968 and 1972, however, there was an explosion of piracetam (PIR) research which uncovered its ability to facilitate learning, prevent amnesia induced by hypoxia and electroshock, and accelerate EEG return to normal in hypoxic animals. (1) By 1972 700 papers were published on PIR. (1) Yet already...
  • Deprenyl - Extending Life Span

      DEPRENYL- EXTENDING LIFE SPAN By James South MA   Deprenyl is a drug that was discovered around 1964-65 by Dr. Joseph Knoll and colleagues. It was originally developed as a psychic energizer, designed to integrate some amphetamine-like brain effects with antidepressant effects. (1) Also known as L-deprenyl, (-)-deprenyl, and selegiline, deprenyl (DPR) has been intensively researched over the past 36 years - many hundreds of research papers on DPR have been ...
  • Tired of Being Tired?

    Tired of Being Tired? According to Dr. Michael Schmidt in his book Tired Of Being Tired, chronic fatigue, tiredness and low energy plague millions of people in the Western world. Indeed, fatigue, chronic tiredness and low energy are the most common reasons which lead people to seek medical care. Dr. Schmidt notes that a 1987 survey found that 24% of adults who visit primary care health clinics "always feel tired" (1). Constant fatigue and low energy are not restricted t...
  • THE FREE RADICAL THEORY OF AGING

    The Free Radical Theory Of Aging Aging is the seemingly inevitable decline in physiologic function that occurs over time. For all living organisms, the ultimate terminus of aging is the same: death. Dr. Denham Harman, the "father" of the free radical theory of aging, has defined "aging" as the increased probability of death as the age of an organism increases, and diverse adverse physiologic changes accumulate. At least four major theories of aging have been propounded that purport ...
  • Beating Attention Deficit Disorder

      Beating Attention Deficit Disorder (or Nutrition and Nootropics For Focus & Attention) By James South MA   "Concentration" denotes the ability to sustain focused attention on a given object, external (such as people or rocks or colors), or internal (such as thoughts, feelings or sensations). The power of concentration also involves the ability to screen out irrelevant distractions that might divert or disrupt sustained, focused attention. Although animals ca...
  • NADH, The Body And Mind Energizer

    NADH, The Body And Mind Energizer NADH is the abbreviation used for Nicotinamide Adenine Dinucleotide, one of the most important coenzymes in the human brain and body. A coenzyme is the active, or working form of a vitamin. NADH is the reduced (electron- energy rich) coenzyme form of vitamin B3, while NAD is the oxidized (burned) coenzyme form of B3. NAD and NADH are converted into each other in numerous different metabolic activities. In some metabolic reactions it is ...
  • Growth Hormone, The Real "Fountain of Youth!"

    Growth Hormone, The Real "Fountain of Youth!" On July 5th 1990, America's most prestigious medical journal, the New England Journal of Medicine, published a human clinical study that changed the world of anti-aging medicine forever. Daniel Rudman, MD and colleagues reported the results of their 6-month trial of synthetic human growth hormone (HGH) with 12 elderly men, aged 61 to 81. Astoundingly, without any change in diet, exercise, lifestyle, smoking etc., the 12 men ...
  • Excitotoxins: The Ultimate Brainslayer

    Excitotoxins: The Ultimate Brainslayer Glutamic acid (also called "glutamate") is the chief excitatory neurotransmitter in the human and mammalian brain (1-3). Glutamate (GLU) neurons make up an extensive network throughout the cortex, hippocampus, striatum, thalamus, hypothalamus, cerebellum, and visual/auditory system (4). As a consequence, GLU neurotransmission is essential for cognition, memory, movement and sensation (especially taste, sight, hearing) (3). GLU and its bio...
  • Discover The Regenerative Effects of GHB, the Elixir of Life!

    Discover The Regenerative Effects of GHB, the Elixir of Life! GHB (Gamma-Hydroxybutyric Acid) is a hydroxylated form of the short-chain fatty acid. GHB is also closely related to GABA (Gamma-Aminobutyric Acid), the chief inhibitory neurotransmitter of the mammalian nervous system. GHB was first synthesised in 1960 by H. Laborit, a French physician. Laborit was interested in studying the action of GABA in the nervous system, but GABA was known to be unable to cross the blood-...
  • DHEA - The Next Generation

    DHEA - The Next Generation Dehydroepiandrosterone (DHEA), in its sulphated form (DHEA-S), is the most plentiful adrenal steroid circulating in the human bloodstream. Along with the major human glucosticoid, cortisol, DHEA is produced in the adrenal cortex. DHEA circulates primarily as DHEA-S, which is generally metabolically inactive. As cells take DHEA-S from the blood, they reconvert it into DHEA, and possibly other metabolites. The pregnenolone metabolite, 17-hydroxypregnol...
  • Nootropics - Reviewing The Smart-Drugs

    Nootropics - Reviewing The Smart-Drugs Over 30 years have passed since the "Nootropic Revolution" quietly began with the development of Piracetam (PIR) in the late 1960's. The second wave of this pharmacologic revolution occurred in the late 1970's with the development of Oxiracetam (OXR), Pramiracetam (PRM) and Aniracetam (ANR). The PIR-nootropics were revolutionary in at least two ways. They combined physiological and medical efficacy with a virtual absence of toxici...
  • L-Tryptophan, Nature's Answer To Prozac ®

    L-Tryptophan, Nature's Answer To Prozac® The "serotonin deficiency syndrome" is one of the most common and widespread disorders of human psychobiology in the modern world. Prozac ® allegedly increases the amount of serotonin in the synaptic gap that slightly separates nerve cells from each other. (For more on the "allegedly" see the excellent book; Talking Back To Prozac by psychiatrist, Peter Breggin). Greater amounts of serotonin in the synaptic gap increases commu...
  • Laetrile - The Answer to Cancer?

    Laetrile - The Answer to Cancer? The anti-cancer drug Laetrile is one of the most controversial subjects in the history of medicine. Laetrile's most ardent proponents consider it to be a natural cancer cure, literally built in to the normal "vitamin architecture" of mammalian food supplies as the primary natural exogenous cancer control for humans and animals. They have called Laetrile "vitamin B17." (1) Laetrile's opponents consider it, quite simply, as a "toxic drug that is not ef...
  • Idebenone - The Ultimate Anti-Aging Drug?

    Idebenone - The Ultimate Anti-Aging Drug? Idebenone (IDB) is a synthetic analog (variant) of one of life's most essential biochemicals, coenzyme Q10 (CoQ10). CoQ10 is an important antioxidant component of the lipid (fatty) membranes that surround all cells, as well as the lipid membranes surrounding the various organelles ("little organs"), such as mitochondria and microsomes, inside cells. CoQ10 is also an important member of the "Electron Transport Chain" (ETC) within...
  • The Mitochondrial Theory of Aging

    The Mitochondrial Theory of Aging The mitochondrial theory of aging (MTA) was first proposed in 1972 by Denham Harman, the "father" of the free radical theory of aging (FRTA) (1). The MTA was further refined and developed in 1980 by Jaime Miquel (2). There is such a strong connection between the MTA and the FRTA that they are often discussed together as if the MTA was just one f...
  • James South - My Personal Supplement Regime

    James South - My Personal Supplement Regime Since 1971, at age 23, I have been pursuing the "elixir of life" and the "fountain of youth." I suffered many severe health problems from infancy, including disabling allergies and asthma; severe arthritis of the knees; motion sickness so severe I would sometimes vomit riding in the car; and neuromuscular balance and co-ordination problems that would frequently cause me to trip going upstairs, or even over my own feet. By the t...
  • Biostim - Boosting the Immune System

    Biostim - Boosting the Immune System Biostim, also known as RU-41740 or C1740, is a unique immunomodulator. It is a compound extracted from the cell wall of a bacteria-Klebsiella pneumoniae - consisting mainly of two large glycoproteins (7,14). Biostim has been widely used in France to treat a variety of infectious conditions since 1982. Biostim has been extensively researched through human clinical (1-14), animal experimental (15-25), and in vitro cell studies (26-39) since 1...
  • Aging and Immunity by James South

    Aging and Immunity We live in a world of entropy. Entropy is the tendency of complex structures to gradually decay or break down with time. Entropy is one of the brute facts of existence. It is "codified" as one of the basic laws of physics: the second law of thermodynamics, which governs both living and inanimate matter. We humans normally call the process of entropy "ageing." The anti-ageing movement is literally an anti-entropy movement. Modern science has discovere...
  • Weight Loss, The Anti-Aging Way

    Weight Loss, The Anti-Aging Way Weight loss and dieting is a perennial subject of conversation, TV talk shows, best-selling books, and even trips to the doctor. And no wonder. In spite of the widespread introduction of "low fat", "no fat", and "reduced fat" foods and snacks throughout the 1990's, obesity has reached epidemic proportions in much of the Western world. Obesity (defined as being 20% or more over "ideal" or "normal" weight for one's size) is now estimated to afflic...
  • Beating Depression, with Alternative Anti-aging Therapies

    Beating Depression, with Alternative Anti-aging Therapies Depression is one of the most widespread illnesses in the Western world, yet it is also one of the most misunderstood and under treated health problems. Approximately 10-14 million people are medically depressed in the U.S. in any given year, yet only one third of depressives receive treatment (1). "Depression is just as socially debilitating as coronary artery disease, and more debilitating than diabetes mellitus or ar...
  • 5-HTP, Prozac's true alternative

    5-HTP, Prozac's true alternative 5-HTP, or 5-hydroxytryptophan (Oxitriptan) is the less well known cousin of serotonin (5-HT), one of the most important brain neurotransmitters. 5HTP vs. Tryptophan L-Tryptophan is first converted to 5-HTP in nerve cells by a vitamin B3 dependant enzyme, and then 5-HTP is converted to 5-HT by a vitamin B6 dependant enzyme. Yet thanks to modern science, we can now take preformed 5-HTP, with many consequent advantag...